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Meryl Streep stars in Silkwood, released in 1983.

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The screenplay for Ephron’s second film, Heartburn, was based on a semi-autobiographical novel of the same name.

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Meg Ryan talks to Billy Crystal in a scene from the iconic When Harry Met Sally.

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Ryan starred with Tom Hanks in 1993’s Sleepless in Seattle.

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Together again: Hanks and Ryan in a scene from You've Got Mail, released in 1998.Warner Bros.

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Interact with The Globe