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Press release from Business Wire

Illumina to Provide Next-Generation Sequencing (NGS) Technologies to Quest Diagnostics

<p class='bwalignc'> <i>Quest to Use Illumina NGS Platform to Create New Lab Test Services</i> </p>

Thursday, January 09, 2014

Illumina to Provide Next-Generation Sequencing (NGS) Technologies to Quest Diagnostics

06:30 EST Thursday, January 09, 2014

SAN DIEGO (Business Wire) -- Illumina, Inc. (NASDAQ:ILMN) today announced it has entered into a multi-year licensing agreement with Quest Diagnostics (NYSE: DGX), the world's leading provider of diagnostic information services, related to the use of Illumina's next-generation sequencing technology for clinical laboratory testing.

Among the terms, Quest will have broad rights to use Illumina's sequencing and genotyping technology, including the MiSeq® platform and related consumables, to develop, validate and offer molecular laboratory-developed tests for several disease states to clinicians in the United States. Quest also has rights to use the Illumina equipment as biomarker test services in clinical trials performed on behalf of its pharmaceutical, biotechnology and other clients.

“Quest's science and innovation strategy is focused on accelerating the introduction of clinically meaningful diagnostic solutions that aid the management of the individual patient across a continuum of care, promoting better outcomes,” said Jay Wohlgemuth, M.D., Senior Vice President, Science and Innovation, Quest Diagnostics. “Investing in next-generation sequencing, which is increasingly used in several clinical areas as well as clinical trials, is a key element of our strategy. Illumina is a leader in NGS innovation, and this new broad agreement will give us a greater level of flexibility to build on our record of success in NGS to include several diseases where sequencing-based molecular testing can meaningfully improve clinical care.”

In 2013, Quest introduced new clinicaltesting services based on Illumina next-generation sequencing technology under limited agreements. The new agreement broadens the range of applications for which Quest may use the Illumina technology, including several cancers and neurological and women's health disorders.

DNA sequencing is a process that determines the order of individual nucleotides of DNA molecules across a single gene, several genes or a full genome. Unlike older technologies, next-generation sequencing platforms can sequence multiple molecules simultaneously, providing greater information about the genetic basis of disease for lower cost.

“We are excited to support Quest's further expansion into next-generation sequencing,” said Nick Naclerio, Illumina's Senior Vice President of Corporate and Venture Development. “Quest's advanced development capabilities and vast clinician network will help bring the power of next-generation sequencing to an ever larger range of patients around the U.S.”

About Illumina

Illumina (www.illumina.com) is a leading developer, manufacturer, and marketer of life science tools and integrated systems for the analysis of genetic variation and function. We provide innovative sequencing and array-based solutions for genotyping, copy number variation analysis, methylation studies, gene expression profiling, and low-multiplex analysis of DNA, RNA, and protein. We also provide tools and services that are fueling advances in consumer genomics and diagnostics. Our technology and products accelerate genetic analysis research and its application, paving the way for molecular medicine and ultimately transforming healthcare.

Forward-Looking Statements

This release may contain forward looking statements that involve risks and uncertainties. Important factors that could cause actual results to differ materially from those in any forward-looking statements are detailed in our filings with the Securities and Exchange Commission, including our most recent filings on Forms 10-K and 10-Q, or in information disclosed in public conference calls, the date and time of which are released beforehand. We do not intend to update any forward-looking statements after the date of this release.

Illumina, Inc.
Investors:
Rebecca Chambers, 858-255-5243
rchambers@illumina.com
or
Media:
Jennifer Temple, 858-882-6822
pr@illumina.com

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