Globe and Mail Update Last updated on Tuesday, Mar. 31, 2009 09:18PM EDT
• Tuberculosis is caused by bacteria that usually attack the lungs and are spread through the air when a person with the disease coughs or sneezes, much like the common cold
• About one-third of the world's population is infected with the bacilli
• Most carriers have "latent" or inactive TB, which means they are symptom free and not contagious; 5-10 per cent of patients become sick and contagious with the "active" form of the disease
• Symptoms include a cough, sometimes with blood or sputum, chest pains, weakness, weight loss, fever and night sweats
• The WHO attributes 1.5-million deaths in 2006 alone to the disease
• The Public Health Agency of Canada reported 1,621 cases of new active and relapsed TB in 2006, an average of about five cases for every 100,000 people; First Nations and homeless communities are particularly vulnerable
• The most recent numbers from Statistics Canada suggest at least 70 people died across Canada in 2004 of TB-related causes
• Southeast Asia and sub-Saharan Africa are two of the world's TB hot spots
• People who are HIV-positive and infected with TB bacilli are much more likely to become sick. Without treatment, about 90 per cent will die within months of contracting TB. About a third of all people living with HIV/AIDS are co-infected with TB
• Treatment involves a six-month course of antibiotics, up to two years for multidrug-resistant strains
• Drug-resistant TB is caused by inconsistent or partial treatment with antibiotics
• Multidrug-resistant TB (MDR-TB) is resistant to at least isoniazid and rifampicin, the two most powerful anti-TB drugs. It's especially prevalent in the former Soviet Union.
• Extensively drug-resistant (XDR) TB is the most serious form of the disease
Compiled by Brodie Fenlon. Sources: World Health Organization, Canadian Lung Association, The Canadian Press
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