Wheat – the “staff of life” – is looking downright unhealthy.
Naturopaths who used to rhapsodize over stone-ground sourdough are advising clients to treat wheat like a biohazard. And ever since Oprah, Gwyneth and the Old Spice Guy (a.k.a. Isaiah Mustafa) started raving about “detoxing” from wheat, it seems everyone has been going gluten-free.
Gluten (Latin for “glue”) sounds like something you’d want to be free of – until you grasp the implications. Gluten is a protein found in rye, barley and wheat. It’s what makes bread chewy and cakes moist. It fills beer with malty goodness. Amazing stuff.
But the very thing that gives baked goods that spring may be the culprit behind an array of health problems, including diarrhea, eczema, headaches, joint pain and depression, researchers suggest.
No wonder so many people are talking about having “gluten issues.”
Although the symptoms may seem nebulous, gluten sensitivity is a real condition, says Alessio Fasano, director of the University of Maryland Center for Celiac Research. Dr. Fasano says gluten sensitivity is part of a spectrum that includes wheat allergy and celiac disease, an autoimmune disorder that attacks the small intestine when even trace amounts of gluten are consumed.
About one in 100 people has celiac disease, and with it, increased risk of osteoporosis, infertility and intestinal cancers, according to the Mayo Clinic.
But the prevalence of non-celiac gluten intolerance is unknown, Dr. Fasano says, adding that medical knowledge of gluten sensitivity today is where it was with celiac disease 10 years ago. “The field is very foggy.”
Until a biomarker for gluten sensitivity is found, doctors must rely on a gluten-free diet for diagnosis, Dr. Fasano says. If, after testing negative for celiac disease and wheat allergy, patients’ symptoms improve after one month of avoiding even a speck of gluten, they are considered gluten sensitive, he says.
Published studies of gluten sensitivity tend to be small, including a recent double-blind randomized trial involving 34 patients at Monash University in Victoria, Australia. The research, published in January in The American Journal of Gastroenterology, found that gluten triggered symptoms in non-celiac patients with gastrointestinal problems. It concluded that “non-celiac gluten intolerance may exist.”
Alternative health practitioners are far more convinced.
Vikki Petersen, a chiropractor, clinical nutritionist and author of The Gluten Effect, estimates that up to 40 per cent of the population have some form of gluten sensitivity. The figure is based on clinical observations at her wellness centre in Sunnyvale, Calif., as well as statements made by Enterolab in Dallas, she says.
Enterolab is a private laboratory that offers a “gluten sensitivity stool and gene panel” test on its website for $369 (U.S.).
Gluten sensitivity affects all systems in the body and may lead to recurrent miscarriage, skin disorders, anxiety, migraines, digestive problems and premature death, Ms. Petersen says. “The human body is actually not designed to digest this protein.”
She points to an analysis of mortality in 35,000 Swedish patients from 1969 to 2008, published in the Journal of the American Medical Association. The study included patients with inflammation of the small intestine, celiac disease or “latent celiac disease” – those with elevated gluten antibodies in a blood test but a negative intestinal biopsy. Compared with the general population, the risk of death for patients with gluten-related disorders was “modestly increased,” the study concluded.
For the gluten-free brigade, the Swedish study is proof that gluten is toxic.
But Dr. Fasano cautions against confusing atypical, latent or potential celiac disease with gluten sensitivity, which by his definition rules out all forms of celiac disease and wheat allergy.
Dr. Fasano says he disagrees with assertions that a third of North Americans have gluten sensitivity. “I have a really hard time believing that we are plagued by this.”
