FRANK JORDANS and MARIA CHENG
GENEVA — Associated Press Published on Tuesday, May. 19, 2009 8:19AM EDT Last updated on Thursday, Jun. 11, 2009 7:01AM EDT
The World Health Organization says making a swine flu vaccine appears to be more difficult than experts first thought.
The acknowledgment comes as health officials from around the world, including Canada's Health Minister Leona Aglukkaq, gathered in Geneva for the WHO's annual meeting this week.
The organization says experts have told it that manufacturers will not be ready to produce a swine flu vaccine until mid-July at the earliest. Previously, WHO officials had thought production could start in late May. Experts have also found no evidence to suggest regular flu vaccines offer any protection against swine flu.
UN Secretary-General Ban Ki-moon and WHO chief Dr. Margaret Chan met with pharmaceutical companies today.
According to vaccine experts convened by the WHO last week, swine flu virus is not growing very fast in laboratories, making it difficult for scientists to get the key ingredient they need for a vaccine, the “seed stock” from the virus. The outbreak has infected 9,830 people in more than 40 countries, killing 79 of them.
The New York City Health Department is investigating the death of a toddler as a possible swine flu case. The 16-month-old boy died Monday night at Elmhurst Hospital Center in Queens. Hospital officials said he had a high fever when he was brought in.
Health Department spokeswoman Jessica Scaperotti confirmed the investigation but said the agency does not discuss specific cases. It's not yet known how long the investigation will take.
On Sunday, a public school assistant principal named Mitchell Wiener became the city's first swine flu death. Hospital and city officials say complications besides the virus probably played a part in Mr. Wiener's death, but his family has said he suffered only from gout, a joint disease.
Vaccine experts have estimated that under the best conditions, they could produce nearly five billion doses of swine flu vaccine over a year after beginning full-scale production. In that situation, the UN might have access to up to 400 million doses for poor countries. The rest of the vaccines would presumably go to wealthy contras who have already signed deals to get the pandemic vaccine as soon as it is available.
Mass producing a pandemic vaccine would be a gamble, as it would take away manufacturing capacity for the seasonal flu vaccine that kills up to 500,000 people each year. Some experts have wondered whether the world really needs a vaccine for an illness that so far appears mild.
Dr. Chan said Monday it would be impossible to produce enough vaccine for all 6.8 billion people on the planet. That suggests a possible global scramble where rich countries outbid poorer nations for the vaccine, leaving them unprotected against the virus.
“It is absolutely essential that countries do not squander these precious resources through poorly targeted measures,” said Dr. Chan.
Unlike other countries such as Britain, the United States has so far refrained from reserving its share of any new vaccine.
“At this point we have not placed orders for vaccine,” U.S. Health and Human Services Secretary Kathleen Sebelius told reporters in Geneva. “There is still so much uncertainty about this virus that it is really premature for us to even make a determination of how many people would appropriately be vaccinated, in what order, how many doses would be required, and at what point.”
These are the issues Mr. Ban and Dr. Chan will discuss with vaccine makers, believed to include top producers Sanofi-Aventis, GlaxoSmithKline and Baxter International as well as drug makers from developing countries.
On Monday, dozens of governments lobbied WHO to tread carefully before next raising its swine flu alert to the highest pandemic level of phase 6. The level currently stands at phase 5 — saying a global outbreak is “imminent.”
Britain, Japan, China and others said Monday that declaring a global outbreak could cause unnecessary panic and confusion, especially since the virus has turned out to be less deadly than feared.
The expert group emphasized that WHO's declaration of a pandemic should not automatically force vaccine makers to switch from making regular flu vaccine to pandemic vaccine. In addition, they said even if swine flu vaccine production began, that did not mean that countries should start immunizing large groups of people.
The experts told WHO that it should come up with targeted advice on which groups of people need the vaccine the most and should get it first. They also planned to meet again in several weeks to decide whether large-scale production of swine flu vaccine should begin.
Since the outbreak began last month, 79 people have died from the disease — 72 in Mexico, five in the U.S., one in Canada and one in Costa Rica, WHO says.
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