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President John F. Kennedy in the Oval Office of the White House in Washington, Feb. 19, 1961. Though the Cuban Missile Crisis took place over a year later, the image has become an iconic representation of what has been characterized as the loneliest job in the world. It’s been more than 50 years since the confrontation between the U.S. and the Soviet Union over the positioning of nuclear missiles in Cuba.GEORGE TAMES/The New York Times

Aug. 13, 1961

East German authorities begin construction of the Berlin Wall, cutting off West Berlin from the rest of West Germany. East German citizens can no longer cross to the non-communist West.

Oct. 14, 1962

U.S. surveillance aircraft find evidence of nuclear missile sites in Cuba, precipitating a Cold War crisis that over 13 days brings the United States and the Soviet Union to the brink of war.

June 26, 1963

President Kennedy visits the Checkpoint Charlie crossing point and sees the Berlin Wall, before speaking to an enthusiastic crowd of 450,000 in front of West Berlin's city hall.

Aug. 28, 1963

Martin Luther King delivers his "I have a dream" speech at the Lincoln Memorial in Washington.

Oct. 7, 1963

President Kennedy signs the Limited Nuclear Test Ban Treaty with the United Kingdom and Soviet Union, outlawing testing in the atmosphere, in space and under water.

Nov. 1, 1963

Vietnam's leader Ngo Dinh Diem is ousted in a military coup with U.S. encouragement, and later executed.

Nov. 22, 1963

President Kennedy is assassinated.

June 12, 1987

In a speech at Berlin's Brandenburg Gate to mark the city's 750th anniversary, U.S. President Ronald Reagan calls on Soviet leader Mikhail Gorbachev to "tear down this wall."

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