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Russell Martin high fives Roberto Osuna after defeating the New York Yankees at Yankee Stadium on Wednesday.Brad Penner

Russell Martin hit his first two home runs of the season, Michael Saunders also went deep and the Toronto Blue Jays finally broke out their big bats again Wednesday night, halting the New York Yankees' six-game winning streak with an 8-4 victory.

Marco Estrada took a two-hitter into the seventh inning and the last-place Blue Jays won for the fourth time in six games following an 0-5 slide.

The defending AL East champions, who led the majors with 891 runs last season, batted .230 and averaged only 3.5 runs over their previous 16 games. The slump prompted manager John Gibbons to juggle his lineup in unusual ways, putting power hitter Jose Bautista in the leadoff spot with sluggers Josh Donaldson and Edwin Encarnacion right behind him.

They hadn't produced much there, but this time Toronto got an early two-run double from slumping No. 9 batter Ryan Goins and pulled away with two homers off reliever Chasen Shreve in a four-run seventh.

Ivan Nova (3-2) threw well again for New York (22-23) but lost for the first time in four starts since moving from the bullpen to the rotation. Trailing 3-1 with two outs in the seventh, he was pulled after hitting Encarnacion with a pitch. Shreve quickly let the game get away by giving up two-run homers to Saunders and Martin.

On an 86-degree night at Yankee Stadium, Chase Headley and Didi Gregorius hit successive homers in the seventh off Estrada (2-2), who yielded four hits and three runs while walking four in seven innings.

The right-hander loaded the bases with nobody out in the third but limited the damage to one run on Brett Gardner's RBI groundout.

Pinch-hitter Austin Romine homered on the first pitch from Blue Jays reliever Chad Girodo in the ninth. Romine's only other major league home run came in August 2013.

Martin also ended a long drought with his leadoff shot to left field against his former team in the sixth. It was the first home run for Martin since Oct. 2 against Tampa Bay. He went 124 at-bats this season without connecting.

Martin began the night batting .172 with one extra-base hit, a double. He had his 11th career multihomer game, third with Toronto and first since Sept. 11, 2015, at Yankee Stadium.

Encarnacion added an RBI single in the eighth.

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