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LeSean McCoy #25 of the Philadelphia Eagles runs for a touchdown against the Dallas Cowboys in the second half at AT&T Stadium on November 27, 2014 in Arlington, Texas.Tom Pennington/Getty Images

LeSean McCoy is looking more like the NFL rushing champion of a year ago, and Mark Sanchez is getting more comfortable in Philadelphia's offence.

McCoy ran for 159 yards and a touchdown, Sanchez had his first scoring run in almost three years and the Eagles beat the Dallas Cowboys 33-10 in a Thanksgiving battle of NFC East co-leaders Thursday.

The Eagles (9-3) opened with quick drives of 80 and 88 yards for touchdowns. They took sole possession of the division lead with four games remaining, including a rematch in less than three weeks.

Tony Romo looked ragged in the first quick turnaround for his surgically repaired back as the Cowboys (8-4) lost their third successive home game.

McCoy, who led the NFL with 1,604 yards last season, had his fourth 100-yard game in the past seven and secured his fourth 1,000-yard season since 2010.

Although his deficit to Dallas's DeMarco Murray in the rushing race is probably insurmountable, McCoy outgained Murray, who was held under 100 yards for just the second time this season.

Murray finished with 73 yards and Dallas's only touchdown on 20 carries, the last a six-yard loss when he was dropped by Mychal Kendricks on fourth-and-one early in the fourth quarter.

Making his fourth start since Nick Foles was sidelined by a broken collarbone, Sanchez was 9 of 11 for 99 yards in the first quarter. That included a 27-yard scoring pass to Jordan Matthews when Sanchez hit the rookie in stride on a crossing route for a 14-0 lead. Sanchez finished 20 of 29 for 217 yards with a touchdown and no interceptions.

Murray had room to run at times but couldn't break one longer than 9 yards. Romo had time to throw most of the day, but one time in the first half tossed a third-down pass to nobody in particular, giving the ball back to the Eagles when the Cowboys were having trouble stopping them.

Romo was sacked four times and finished 18 for 29 for 199 yards with two interceptions and no touchdowns, snapping a streak of 38 games with one TD pass.

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