Malaysia's world number one Nicol David will start her bid for a record-equalling fifth World Open squash title against Farah Abdel Meguid on Saturday after the Egyptian youngster ousted world junior champion Amanda Sobhy.
The 18-year-old Abdel Meguid, ranked 103 in the world, beat American teenager Sobhy 11-8 8-11 13-11 11-9 in Friday's final qualifying round to reach the main draw along with compatriots Nour El Tayeb, Nour El Sherbini and Kanzy El Dafrawy.
England's world number four Alison Waters faces Egyptian qualifier El Dafrawy while Egypt's world number six Omneya Abdel Kawy plays qualifier Tania Bailey of England.
Last year's runner-up Natalie Grinham of Netherlands, ranked 13th, meets Malaysia's Low Wee Wern in her first round match.
World number two Jenny Duncalf of England has a bye to the second round where she will face either Egypt's Engy Kheirallah, ranked 11th in the world, or New Zealand's Joelle King.
David, who has won four World Open titles in the last five years, is unbeaten this year and victory at the championship would give her a third straight world title and a fifth overall to match the haul of Australia's Sarah Fitz-Gerald.
Fitz-Gerald collected her titles between 1996 and 2002.