The Victorian-era detective series Murdoch Mysteries is coming to an end.
Citytv says the show's upcoming fifth season will be its last.
The network says production is under way on new episodes, which kick off in the Yukon and will introduce Dr. Julia Ogden's ambitious new protege.
The weekly series revolves around Det. William Murdoch and crime-solving forensic techniques that were radical in the late 1800s.
Guest stars slated for the final season include Canadian soprano Measha Brueggergosman, Aaron Ashmore ( Warehouse 13, Smallville) and British actress Jill Halfpenny ( Coronation Street).
Producer Christina Jennings says she is sad to see the show end but is looking forward to a "fulfilling conclusion." No airdate has been set.
"While we are sad to contemplate the end of Murdoch Mysteries, we are grateful to Rogers and Citytv for believing in the series and taking this journey with us over the past seven years," Jennings said Tuesday in a release.
"We've watched the show grow with the passionate support of audiences in Canada and around the world, and look forward to bringing the storyline to a fulfilling conclusion for fans during our final season."
One of the show's biggest champions was Prime Minister Stephen Harper, who has said he never missed an episode and even made a cameo on the show earlier this year.
Citytv says the final season opens with Det. Murdoch, played by Yannick Bisson, investigating a murder in the Yukon during the Klondike Gold Rush.
New episodes will present the detective with "fresh frustrations" in his relationship with Julia.
Upcoming guest stars include Ashmore as author Jack London and Halfpenny as Elizabeth Bryant, a tough-as-nails hotel owner who finds herself accused of murder.
Murdoch Mysteries is the latest cancellation in a wave of Canadian cuts.
Earlier this month CTV said it was ending its sitcoms Dan for Mayor and Hiccups, as well as the reality competition So You Think You Can Dance Canada.