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A select viewing guide for Wednesday, March 28

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REALITY Leave It to Niecy TLC, 8 p.m. ET; 10 p.m. PT Who is Niecy Nash and why does she have her own reality series? The fortysomething actress has built a career on playing brassy support roles on TV series like The Bernie Mac Show and That's So Raven, and was also a contestant on the 10th season of Dancing with the Stars. This new series documents Niecy's recent marriage to Jay Tucker and the subsequent blending of their respective families, which includes her three children and his young son. And does forced drama arise in this mixed family? In tonight's first show, Niecy tries to force her spoiled kids to bond with their new stepfather. In the second show, she tries to get the entire family eating healthily, but everyone is too hooked on junk food. You go, girl!

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COMEDY Only Fools and Horses Vision, 8:30 p.m. ET/PT Treat yourself to some old-school British TV comedy. First broadcast from 1981 to 1991, this BBC sitcom rides entirely on the performance of David Jason, perhaps better known to viewers as Detective Jack on the crime drama A Touch of Frost. On this show, Jason is the marvellous rapscallion Derek (Del Boy) Trotter, an ambitious market trader forever on the lookout for the big payday. In most episodes, his efforts are waylaid by his dim brother Rodney (Nicholas Lyndhurst). In tonight's third-season outing, Derek delves into the art-dealing world and falls for a lovely woman named Miranda – unaware that she's an undercover detective. Watch your back, mate.

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SCIENCE NOVA PBS, 9 p.m. ET/PT Science has made tremendous strides in DNA research, but what are the benefits for the average person? Tonight's episode demonstrates how scientists have been able to identify and neutralize certain genetic abnormalities of once-deadly conditions. The program profiles a cancer patient who seems to have cheated death and a cystic fibrosis sufferer now breathing freely on his own. At the same time, the report examines the moral dilemmas created by the new technology. Does it help people to know their genetic blueprint and what happens if the information falls into the wrong hands? Watch and get smarter.

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MOVIE All Fall Down TCM, 10:30 p.m. ET; 7:30 p.m. PT Although more or less retired from the movie business today, Warren Beatty was one of the biggest movie stars of the sixties. The handsome actor spent the first half of his career playing heartless rogues, due in large part to his convincing portrayal in this 1962 drama. Beatty morphs effortlessly into the skin of self-centred Berry-Berry (yes, that's his real name), who bounces from one woman to the next with no compunction about emptying their bank accounts in the process. At home, Berry-Berry has no love for his controlling mother (Angela Lansbury) or boozing father (Karl Malden), but keeps contact with his younger brother Clint (Brandon de Wilde). All brotherly ties are shattered when the rogue attempts to seduce the lovely Echo (Eva Marie Saint), who has already captured Clint's heart.

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