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Royal Caribbean Cruises Ltd. has cancelled eight cruises out of China through March 4 in response to the coronavirus outbreak in the world’s second-largest economy, the company said on Tuesday.

The company said it expects the cancellations and some modifications to its itineraries to reduce earnings by 25 US cents a share.

Royal Caribbean also said it would deny boarding to people who had visited mainland China or Hong Kong over the past 15 days. It will also screen Chinese and Hong Kong passport holders and people showing flu-like symptoms.

The company had earlier this month cancelled three trips scheduled for February, after consultation with health authorities over the spread of the virus, which has killed more than 400 people and infected thousands in China.

The Miami-based company forecasts 2020 adjusted profit to be between US$10.40 and US$10.70 a share, excluding any potential impact from the coronavirus outbreak, largely above Wall Street expectations of US$10.47, according to IBES data from Refinitiv.