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Two health networks in Toronto say shortages of COVID-19 vaccine are forcing them to limit or close immunization clinics.

Scarborough Health Network says it will be closing its Centennial College and Centenary hospital clinics today.

University Health Network says it has had to pause registration for appointments for adults over 18 who qualify for vaccination based on their postal code.

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Both organizations say they will reopen their clinics as soon as they receive more vaccines.

The networks say they are contacting everyone whose vaccination appointment was cancelled by the supply shortage and will rebook appointments as soon as possible.

The clinics run by Scarborough Health Network were vaccinating local residents over the age of 50, all Indigenous adults, and health-care workers.

Others eligible for the vaccine at the closed Scarborough locations are chronic home care clients, faith leaders, and people over 18 with high-risk health conditions.

Ontario reported 4,156 new cases of COVID-19 Wednesday and 28 more deaths related to the virus.

Health Minister Christine Elliott says there are 1,254 new cases in Toronto, 593 in Peel Region, and 476 in York Region.

The ministry of health says that 642 people are in intensive care.

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Ontario says more than 112,000 doses of a COVID-19 vaccine were administered since yesterday’s update.

Sign up for the Coronavirus Update newsletter to read the day’s essential coronavirus news, features and explainers written by Globe reporters and editors.

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