DescriptionTrillium Therapeutics Inc. is a clinical stage immuno-oncology company developing innovative therapies for the treatment of cancer. The company's lead program, SIRPaFc (TTI-621), is a fusion protein that consists of the CD47-binding domain of human SIRPa linked to the Fc region of a human immunoglobulin (IgG1). It is designed to act as a soluble decoy receptor, preventing CD47 from delivering its inhibitory (`do not eat`) signal. Neutralization of the inhibitory CD47 signal enables the activation of macrophage anti-tumor effects by pro-phagocytic (`eat`) signals. A Phase 1 clinical trial (NCT02663518) evaluating SIRPaFc is ongoing. Trillium also has a proprietary medicinal chemistry platform, using unique fluorine chemistry, which permits the creation of new chemical entities from validated drugs and drug candidates with improved pharmacological properties.
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|Period||Period Low||Period High||Performance|
|1-Month|| 10.42 +0.77% increase |
| 14.93 -29.67% decrease |
| -2.54 (-19.48%) decrease |
|3-Month|| 10.42 +0.77% increase |
| 18.38 -42.87% decrease |
| -7.59 (-41.96%) decrease |
|52-Week|| 2.50 +320.00% increase |
| 20.96 -49.90% decrease |
| +4.70 (+81.03%) increase |