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What do you do when your depression doesn’t respond to traditional treatments? Especially when that depression is severe and causes suicidal thoughts? For author Anna Mehler Paperny, that meant turning to ketamine.

Often thought of as just a party drug, evidence for the use of ketamine as a treatment for depression is growing. Anna details her journey navigating the new treatment as a patient, examining how the therapeutic use of psychedelic drugs has changed the way we understand the brain and depression.

If you are having thoughts of suicide, call Kids Help Phone at 1-800-668-6868 or Crisis Service Canada at 1-833-456-4566, or visit

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