The NBA says the Orlando Magic and Toronto Raptors will play a regular-season game in London on Jan. 14.
It will be the sixth league game played at the O2 Arena in the British capital. Before 2011, games in London were only exhibitions.
The trip will mark the Raptors' third European trip in team history. Toronto played back-to-back games versus the New Jersey Nets at The O2 in March, 2011 – the first time NBA regular-season games were held in Europe.
"On behalf of the Raptors organization, we are proud to return to London for NBA Global Games 2016," said Raptors President and general manager Masai Ujiri. "We had a tremendous experience in London in 2011 and look forward to reconnecting with the fans and community.
"This is a wonderful opportunity for us to continue in the NBA's mission to make an impact globally."
The Raptors also participated in NBA Europe Live 2007, which included pre-season games in Rome and Madrid.
Magic coach Scott Skiles says "I remember playing in London with the Magic in 1993 and I am sure our current players will relish this unique opportunity."
The Boston Celtics will take on the Sacramento Kings in Mexico City in a regular-season game on Dec. 3 while Milan, Madrid, Shenzhen, Shanghai and Rio De Janeiro will stage NBA pre-season games which were previously announced.
"We look forward to returning to London next season with a regular-season game between the Orlando Magic and the Toronto Raptors," NBA Commissioner Adam Silver said in a statement.
"This underscores our commitment to growing basketball in the region and to bringing more regular-season basketball to our fans in the UK."
NBA Global Games 2015-16 schedule:
Pre-season: Oct. 6 - Boston Celtics vs. Olimpia Milano in Milan, Italy Oct. 8 - Boston Celtics vs. Real Madrid in Madrid Oct. 11 - Los Angeles Clippers vs. Charlotte Hornets in Shenzhen, China Oct. 14 - Los Angeles Clippers vs. Charlotte Hornets in Shanghai Oct. 17 - Orlando Magic vs. Flamengo in Rio De Janeiro
Regular season: Dec. 3 - Boston Celtics vs. Sacramento Kings, Mexico City Arena in Mexico City Jan. 14 - Orlando Magic vs. Toronto Raptors, The O2 in London
Files from Reuters were used in this report