Minnesota Vikings (2-8) at Atlanta Falcons (6-4)
MINNESOTA plus 10
No Adrian Peterson gives the Vikings no chance.
The pick VIKINGS
Cleveland Browns (4-6) at Cincinnati Bengals (6-4)
CLEVELAND plus 8
Cincinnati quarterback Andy Dalton has a rookie record-tying 15 touchdown passes through 10 games. He won't be slowing down here.
The pick BENGALS
Tampa Bay Buccaneers (4-6) at Tennessee Titans (5-5)
TAMPA BAY plus 4
Titans running back Chris Johnson should find himself back on track against a Tampa rushing defence ranked 26th in the league.
The pick TITANS
Carolina Panthers (2-8) at Indianapolis Colts (0-10)
CAROLINA minus 4
Luckily, Indy fans can watch legendary receiver Marvin Harrison being inducted into the team's ring of honour. Should help distract from the squad's current woes.
The pick PANTHERS
Arizona Cardinals (3-7) at St. Louis Rams (2-8)
Flip a coin.
The pick RAMS
Buffalo Bills (5-5) at New York Jets (5-5)
BUFFALO plus 9
No Fred Jackson. No Donald Jones. In all honesty, Bills quarterback Ryan Fitzpatrick might as well stay at home.
The pick JETS
Houston Texans (7-3) at Jacksonville Jaguars (3-7)
HOUSTON minus 4
Former Heisman Trophy winner Matt Leinart gets his first start since 2009. With the talent around him, he might just do okay.
The pick TEXANS
Chicago Bears (7-3) at Oakland Raiders (6-4)
CHICAGO plus 4
This will be the first opportunity for the Bears faithful to rue quarterback Jay Cutler's broken thumb.
The pick RAIDERS
Washington Redskins (3-7) at Seattle Seahawks (4-6)
WASHINGTON plus 4
The Redskins have won the past five encounters. That should end here.
The pick SEAHAWKS
New England Patriots (7-3) at Philadelphia Eagles (4-6)
NEW ENGLAND minus 4
They may be at home, but Philly's injury problems will prove an insurmountable obstacle.
The pick PATRIOTS
Denver Broncos (5-5) at San Diego Chargers (4-6)
DENVER plus 6
Broncos quarterback Tim Tebow has been clutch in the fourth quarter. San Diego should have put this game away long before then.
The pick CHARGERS
Pittsburgh Steelers (7-3) at Kansas City Chiefs (4-6)
PITTSBURGH minus 11
Quarterback Tyler Palko will get the start, even after the Chiefs claimed Kyle Orton on waivers. It won't make a lick of difference.
The pick STEELERS
New York Giants (6-4) at New Orleans Saints (7-3)
NEW YORK plus 7
Giants quarterback Eli Manning gets a homecoming in New Orleans. That's a good thing, as he'll likely need the support of his family after this encounter.
The pick SAINTS
Last week: 6-7-1