Maria Sharapova of Russia returns a ball to Coco Vandeweghe of the United States during their singles match. Sharapova won the match 6-3, 6-7(3), 6-2.Pavel Golovkin/The Associated Press
The U.S. Tennis Association says Maria Sharapova is pulling out of the U.S. Open on the eve of the tournament because of a leg injury.
It's the second time in three years that the 2006 champion has withdrawn from the year's last Grand Slam event.
Sharapova has not played a match since losing to Serena Williams in the Wimbledon semifinals in July. She withdrew from hard-court tournaments in Toronto and Cincinnati in August, citing a right leg strain.
Sharapova is a five-time major champion who was seeded No. 2 for the U.S. Open, where play begins Monday.
The USTA says Sunday that Daria Kasatkina is the lucky loser who will replace Sharapova in the main draw.