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Democratic presidential candidate former Vice President Joe Biden speaks to members of the press at the National Constitution Center in Philadelphia on March 10, 2020. Biden will publicly address an allegation of sexual assault for the first time in an appearance on morning television Friday.Matt Rourke/The Associated Press

Joe Biden will publicly address an allegation of sexual assault for the first time in an appearance on morning television Friday, after weeks of silence on the issue that had prompted frustration from Democrats and attacks from Republicans seeking to weaken him for a general election contest against U.S. President Donald Trump.

Mr. Biden will discuss the allegation on Morning Joe on MSNBC, according to a Twitter post from the network. The decision followed intensive discussions in the Biden campaign about how to more forcefully confront the allegation.

The planned appearance came as scrutiny of the allegation intensified on Capitol Hill on Thursday, with the Democratic Party’s highest-ranking office-holder expressing support for Mr. Biden’s presidential bid while Republicans weaponized the accusation to attack congressional Democrats as hypocritical.

During her weekly news conference, House Speaker Nancy Pelosi sought to calm anxious Democrats, calling Mr. Biden a person of “great integrity” and saying that there were no records or additional witnesses corroborating the account from Tara Reade, a former aide who worked in Mr. Biden’s Senate office in the early 1990s. Ms. Reade has accused Mr. Biden of assaulting her at a Senate building in 1993, an allegation the Biden campaign says is not true.

“I want to remove all doubt in anyone’s mind: I have a great comfort level with the situation as I see it, with all due respect in the world for any woman who comes forward, with all the highest regard for Joe Biden,” Ms. Pelosi told reporters.

The speaker said she had “complete respect for the whole MeToo movement.” “There is a lot of excitement around the idea that women will be heard and be listened to,” she said. “There is also due process and the fact that Joe Biden is Joe Biden.”

Her comments came as Republicans expanded their attacks against Mr. Biden, the party’s presumptive nominee, as well as a broad number of Democratic candidates, calling them hypocritical on issues of sexual violence, harassment and gender inequality. They also compared the way Democrats have responded to Ms. Reade’s allegation with their response to accusations of sexual assault in 2018 against Brett Kavanaugh during his Supreme Court confirmation hearings.

Already, the Trump campaign has signalled that it plans to make the allegation against Mr. Biden a central part of its campaign narrative, accusing him in a memo Wednesday of “misrepresenting news reports and his own past positions in an effort to put controversies to bed or to level charges against the president.”

At a time when congressional Republicans and their strategists fear being dragged down by Mr. Trump’s handling of the coronavirus crisis, top party leaders see an opportunity to move the political conversation toward a focus on Mr. Biden.

Ms. Pelosi’s Republican counterpart, Representative Kevin McCarthy of California, the minority leader, quickly said her reasoning was insufficient.

“She’s being a hypocrite,” Mr. McCarthy said. “You can’t say one thing about every other time she has commented about any other accusation and now say this is different.”

Republicans circulated remarks Ms. Pelosi made after the confirmation of Mr. Kavanaugh to underscore their point. In a statement at the time, Ms. Pelosi said that in declining to fully investigate the assault allegations against the Supreme Court nominee, Senate Republicans had failed women across America.

“Senate Republicans chose to send a clear message to all women: Do not speak out, and if you do, do not expect to be heard, believed or respected,” she said at the time.

The National Republican Congressional Committee sought to turn down-ballot Democrats into collateral damage, firing off a flurry of emails attacking House candidates, including representatives Cindy Axne of Iowa, Lucy McBath of Georgia and Abigail Spanberger of Virginia.

“During the Kavanaugh hearings, Lucy McBath said, ‘I will not stay silent when women throughout this country are speaking out,’” one e-mail said. “But so far, she’s stayed silent about Tara Reade who has accused Vice-President Joe Biden of sexual assault. Will Lucy McBath be a leader and speak out for ALL women even when it doesn’t politically suit her?”

In an interview with Fox News, Senator Mitch McConnell, the majority leader, said Mr. Biden should release his Senate papers to offer information that could shed light on the alleged assault. Mr. McConnell has not made a similar request of Mr. Trump, who has been accused of sexual assault and misconduct by more than a dozen women who have described behaviour that went far beyond the allegation against Mr. Biden. Mr. Trump has also repeatedly denigrated women over their appearance and intellect.

“When you run for president of the United States, your life is an open book, and I can’t imagine that Vice-President Biden is not going to have to participate in releasing all of the information related to the allegations,” Mr. McConnell said. “It’s a very challenging thing to run for president. And I think everyone who’s done that has realized their entire life is opened up to scrutiny. And I think that’s happening to Vice-President Biden, and they shouldn’t be surprised.”

Mr. Biden’s Senate papers are housed at the University of Delaware but are not open to the public, according to Andrea Boyle Tippett, the university’s director of external relations.

“We are currently curating the collection, a process that we estimate will carry at least into the spring of 2021,” she said in an e-mail. “As the curating process is not complete, the papers are not yet available to the public, and we are not able to identify what documents or files can be found within the collection.”

She confirmed that members of the Biden campaign had gained access to the collection, as reported by Business Insider, but she said that no one from the campaign had looked at the papers since Ms. Reade’s allegations surfaced March 25.

As Republicans stepped up their attacks, Mr. Biden and his campaign had not addressed the issue publicly. Their silence has raised questions among some Democrats about the agility of his campaign operation and its ability to navigate what is widely expected to be a heated and deeply divisive presidential campaign this fall.

It has also frustrated some activists and prominent women’s groups who support Mr. Biden’s bid but have been pushing his campaign to make a public statement on the allegation.

The Biden campaign has told allies that it does not believe the issue is affecting how voters view Mr. Biden and his character. Since Ms. Reade’s allegation surfaced, Mr. Biden has not been asked about it in any interviews. The Biden campaign has not made him available for an interview with The New York Times.

The issue did not come up Thursday during a virtual event Mr. Biden held on Instagram with soccer star Megan Rapinoe.

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