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A police officer walks by the nose of Pan Am Flight 103 in a field near the town of Lockerbie, Scotland, on Dec. 21, 1988.

MARTIN CLEAVER/AP

The family of a Libyan man found guilty of the 1988 Lockerbie plane bombing that killed 270 people will seek to appeal the conviction direct to Britain’s top court after being refused permission by the Scottish Appeal Court, their lawyer said.

Abdel Basset al-Megrahi, an intelligence officer who died in 2012, was jailed for life in 2001 for the murder of 243 passengers, 16 crew and 11 residents of the Scottish town of Lockerbie in the deadliest militant attack in British history.

In January, the Court of Criminal Appeal in Scotland rejected an appeal brought by his family, who had argued that there had been a possible misconduct of justice, and their lawyer Aamer Anwar said on Thursday the same court had now refused permission for them to appeal that decision.

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“I have now instructed our legal team to seek leave to appeal directly to the UK Supreme Court which is the final court of appeal for my father’s case,” Mr. al-Megrahi’s son Ali said in a statement.

“I regard my father Abdelbasset Al-Megrahi as the 271st victim of Lockerbie.”

Pan Am Flight 103 was blown up over Lockerbie in December, 1988, en route from London to New York, carrying mostly Americans on their way home for Christmas.

Mr. al-Megrahi, who denied involvement in the attack, died in Libya in 2012 after being released three years earlier by the Scottish government on compassionate grounds due to prostate cancer.

Former leader Muammar Gaddafi accepted Libya’s responsibility for the bombing in 2003 and paid compensation to families, but did not admit personally ordering it.

However, Mr. al-Megrahi’s family and some relatives of the Scottish victims have always doubted his guilt and Libya’s responsibility, and say the truth has yet to come out.

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